Biofilm Formation and Immunomodulatory Activity of Proteus mirabilis Clinically Isolated Strains

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Biofilm Formation and Immunomodulatory Activity of Proteus mirabilis Clinically Isolated Strains

Urinary tract infections (UTIs) and catheter-associated UTIs (CAUTIs) are the principal hospital-acquired infections. Proteus mirabilis is characterized by several virulence factors able to promote adhesion and biofilm formation and ameliorate the colonization of urinary tract and the formation of crystalline biofilms on the abiotic surface of the urinary catheters. Since, to date, the role of ...

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The Ciprofloxacin Impact on Biofilm Formation by Proteus Mirabilis and P. Vulgaris Strains

BACKGROUND Proteus spp. bacilli belong to opportunistic human pathogens, which are primarily responsible for urinary tract and wound infections. An important virulence factor is their ability to form biofilms that greatly reduce the effectiveness of antibiotics in the site of infection. OBJECTIVES The aim of this study was to determine the value of the minimum concentration of ciprofloxacin t...

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the ciprofloxacin impact on biofilm formation by proteus mirabilis and p. vulgaris strains

conclusions minimum biofilm eradication values of ciprofloxacin obtained in the study are close to the values of the minimal inhibition concentration (mic). results all tested strains formed a biofilm. a value of 1.0 μg/ml ciprofloxacin is mbe50 for the strains of both tested species. an mbe90 value of ciprofloxacin for isolates of p. vulgaris was 2 μg/ml and for p. mirabilis was 512 μg/ml. mat...

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Allicin from garlic inhibits the biofilm formation and urease activity of Proteus mirabilis in vitro.

Several virulence factors contribute to the pathogenesis of Proteus mirabilis. This study determined the inhibitory effects of allicin on urease, hemolysin and biofilm of P. mirabilis ATCC 12453 and its antimicrobial activity against 20 clinical isolates of P. mirabilis. Allicin did not inhibit hemolysin, whereas it did inhibit relative urease activity in both pre-lysed (half-maximum inhibitory...

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O antigens of Proteus mirabilis and Proteus vulgaris strains isolated from patients with bacteremia.

During the period of 1971 to 1979, 172 Proteus mirabilis and 17 Proteus vulgaris strains were collected from blood cultures. Of these strains, 144 could be grouped into 25 O antigens. The most common antigens were O3, O23, O10, O30, and O24, which represented 46.1% of all strains. The O antigen distribution of strains isolated from blood cultures did not differ significantly from that of fecal ...

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ژورنال

عنوان ژورنال: International Journal of Molecular Sciences

سال: 2017

ISSN: 1422-0067

DOI: 10.3390/ijms18020414